Wiwat Chatwongwan

Pinai Nirunrungrueng

Dusit Winaichatsak

Phat Payappanon

Keywords :

oral cancer, survival rate, neck nodal metastasis

Abstract :

The objective of the study was to identify factors influencing the 5-year survival of oral cancer patients. The subjects in this study were patients receiving treatment between 2014 and 2016. Each patient last status was monitored in 2023. Kaplan-Meier and Cox regression analyses were used for data evaluation. For the results, out of the 359 patients studied, the median survival time was 7.62 years. Survival rates at 1-year, 3-year, and 5-year were 81.6%, 63.1%, and 57.5%, respectively. Factors related were tongue carcinoma in the late stage (adjusted hazard ratio, AHR = 2.23, 95% CI [1.12, 4.45], p-value = 0.023), hard palate and upper gum carcinoma in the late stage (AHR = 5.0, 95% CI [1.99, 12.57], p-value = 0.001), early lower gum cancer (AHR = 5.0, 95% CI [1.99, 12.57], p-value = 0.003), and cancer that had spread to the cervical lymph nodes (AHR = 2.29, 95% CI [1.52, 3.46], p-value < 0.001). For conclusion, late-stage carcinomas of the tongue, hard palate, and upper gum, early-stage carcinoma of the lower gum, and neck nodal metastasis were significant factors influencing survival.

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